IPLB-LdFB
Order
Species
Common Name(s)
Gypsy moth
Primary Designation
IPLB-LdFB
Accession No.
CVCL_Z100
Stage
Tissue
Initiator(s)
D. E. Lynn
References
Lynn, D. E., Dougherty, E. M., McClintock, J. T., & Loeb, M. (1988). Development of cell lines from various tissues of Lepidoptera. In: Invertebrate and Fish Tissue Culture (eds. Kuroda, Y., Kurstak, E., Maramorosch, K.); pp.239-242; Japan Sci. Soc.; Tokyo.; Malagoli, D. (2008). Cell death in the IPLB-LdFB insect cell line: facts and implications. Current Pharmaceutical Design, 14(2), 126-130.
Notes
Unique properties: this cell line was tested for on stress-induced cell death; apoptotic IPLB-LdFB cells display all the typical morphologic features, i.e., cell shrinkage, nuclear condensation, DNA fragmentation, nuclear fragmentation and the formation of apoptotic bodies; activity of a caspase-3-like molecule have been seen in apoptotic IPLB-LdFB cells; Sublines: IPLB-LdFB1 and IPLB-LdFB/Gf; Clonal lines: IPLB-LdFB clone 2, 4, 5, and 6.
Medium
IPL-52P + StockP, 10%FBS
Cell Culture Collection
Robert Harrison, USDA, ARS, Invasive Insect Biocontrol and Behavior Laboratory, Beltsville, Maryland, USA.
robert.l.harrison@usda.gov
Status
Microorganism Propagation
Able to replicate Autographa californica multiple nucleopolyhedrovirus (AcMNPV)
